glioblastoma

noun

glio·​blas·​to·​ma ˌglī-ō-ˌbla-ˈstō-mə How to pronounce glioblastoma (audio)
variants or less commonly glioblastoma multiforme
plural glioblastomas also glioblastomata ˌglī-ō-ˌbla-ˈstō-mə-tə How to pronounce glioblastoma (audio) or glioblastomas multiforme or glioblastoma multiformes
: a malignant rapidly growing astrocytoma of the central nervous system and usually of a cerebral hemisphere

Examples of glioblastoma in a Sentence

Recent Examples on the Web
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The startup, Altido Therapeutics, is trying to commercialize a CAR-T cell therapy developed at Massachusetts General Hospital (MGH) for glioblastoma, a nearly always fatal brain tumor. Jason Mast, STAT, 28 Jan. 2026 Temozolomide—the standard of care for glioblastoma—works by depositing a methyl group onto the DNA of cells, specifically on guanine, one of DNA’s four base molecules. Isabella Backman, Hartford Courant, 27 Jan. 2026 In diseases like glioblastoma — diffuse, infiltrative, and resistant — delivery is often the difference between theoretical efficacy and real-life impact. Sanjay Srivastava, Forbes.com, 26 Jan. 2026 Some of these natural compounds are even making their way into human medicine — like a molecule now in phase three clinical trials for treating glioblastoma, an aggressive brain cancer. David L. Coddon, San Diego Union-Tribune, 22 Jan. 2026 See All Example Sentences for glioblastoma

Word History

Etymology

New Latin, from glia glia + blast- + -oma

First Known Use

circa 1923, in the meaning defined above

Time Traveler
The first known use of glioblastoma was circa 1923

Browse Nearby Words

Cite this Entry

“Glioblastoma.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/glioblastoma. Accessed 2 Feb. 2026.

Medical Definition

glioblastoma

noun
glio·​blas·​to·​ma ˌglī-(ˌ)ō-bla-ˈstō-mə How to pronounce glioblastoma (audio)
plural glioblastomas also glioblastomata -mət-ə How to pronounce glioblastoma (audio)
: a malignant rapidly growing astrocytoma of the central nervous system and usually of a cerebral hemisphere
Glioblastoma is the worst grade of malignant glioma, a relatively uncommon but deadly class of brain tumors that kills 97% of those diagnosed within 5 years.Greg Miller, Science

called also glioblastoma multiforme

Last Updated: - Updated example sentences
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